Psychedelic microdosing

Psychedelic microdosing involves consuming sub-threshold doses (microdoses) of serotonergic psychedelic drugs like LSD and psilocybin to potentially enhance creativity, energy, emotional balance, problem-solving abilities, and to address anxiety, depression,^[1] and addiction.^[2][3] This practice has gained popularity in the 21st century.^[4][5] A June 2024 report by the RAND Corporation suggests that among adults in the United States reporting the use of psilocybin in the past year, nearly half reported microdosing the last time they used it.^[6]

LSD and psilocybin are the most commonly used substances for microdosing, with volumetric liquid dosing often employed for precise LSD measurement.^[7][8] A microdose is usually 1/20 to 1/10 of an active dose of a psychedelic drug.^[7][9]

Gender and education significantly influence microdosing prevalence. An online survey revealed that 13% of 2,437 respondents had practiced microdosing, with current microdosers at 4%.^[10] Microdosers typically have lower incomes and education levels, with no specific employment type associated.^[10]

A separate survey of Reddit users found no significant difference in age, sexual orientation, social class, or education level between microdosers and non-microdosers. However, microdosers were more likely to be male, less religious, and reported a lower incidence of anxiety or substance use disorders. They commonly used LSD or psilocybin on a one-day-on, two-days-off schedule.^[11]

• Microdosing
• Nootropic
• Psychedelic therapy
• Neuropsychopharmacology