Hispidin

Hispidin
	Chemical structure of hispidin
Names
	Preferred IUPAC name 6-[(1E)-2-(3,4-Dihydroxyphenyl)ethen-1-yl]-4-hydroxy-2H-pyran-2-one
	Other names 6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone
Identifiers
CAS Number	555-55-5 Y;
3D model (JSmol)	Interactive image; Interactive image;
ChemSpider	13975015 N;
PubChemCID	5353671;
UNII	SSJ18CG55E Y;
CompTox Dashboard(EPA)	DTXSID401017256;
	InChI InChI=1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+ N Key: SGJNQVTUYXCBKH-HNQUOIGGSA-N N;
	SMILES C1=CC(=C(C=C1/C=C/C2=CC(=CC(=O)O2)O)O)O; OC=2/C=C(/C=C/c1ccc(O)c(O)c1)OC(=O)C=2;
Properties
Chemical formula	C13H10O5
Molar mass	246.218 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Hispidin is a natural substance. It can also be synthesized.^[1]

Hispidin 4-O-β-D-glucopyranoside can be found in Pteris ensiformis^[2] whereas hispidin derivatives, such as phellibaumins, can be found in the edible mushroom Inonotus xeranticus^[3] or Phellinus.^[4]^[5] Hispidin is a precursor of fungal luciferin, a compound responsible for light emission by luminous mushrooms.

References

↑Gonindard, C.; Bergonz i, C.; Denier, C.; Sergheraert, C.; Klaebe, A.; Chavant, L.; Hollande, E. (1997). "Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro". Cell Biology and Toxicology. 13 (3): 141–53. doi:10.1023/A:1007321227010. PMID 9088624. S2CID 755744.
↑Chen, Y.; Chang, F.; Lin, Y.; Wang, L.; Chen, J.; Wu, Y.; Wu, M. (2007). "Identification of phenolic antioxidants from Sword Brake fern (Pteris ensiformis Burm.)". Food Chemistry. 105: 48–56. doi:10.1016/j.foodchem.2007.03.055.
↑イ・インギョン；ソク、スンジャ。キム・ワンギュ;ユン・ボンシク (2006) 「キノコInonotusxeranticus由来のヒスピジン誘導体とその抗酸化活性」。ナチュラルプロダクツジャーナル。69 (2): 299–301 .土井: 10.1021/np050453n。PMID 16499338。
↑ Lee, In-Kyoung; Yun, Bong-Sik (2007). "薬用キノコのイノノトゥス属とフェリヌス属に含まれる、ヒスピジン系抗酸化物質の多様性を提供する高酸素化および不飽和代謝物". Bioorganic & Medicinal Chemistry . 15 (10): 3309–14 . doi : 10.1016/j.bmc.2007.03.039 . PMID 17387019 .
↑ Lee, Yeon Sil; Kang, Young-Hee; Jung, Ju-Young; Lee, Sanghyun; Ohuchi, Kazuo; Shin, Kuk Hyun; Kang, Il-Jun; Park, Jung Han Yoon; et al. (2008 年 10 月). " Phellinus linteusの子実体からのタンパク質糖化阻害剤" . Biological & Pharmaceutical Bulletin . 31 (10): 1968– 72. doi : 10.1248/bpb.31.1968 . PMID 18827365 .

[1] Gonindard, C.; Bergonz i, C.; Denier, C.; Sergheraert, C.; Klaebe, A.; Chavant, L.; Hollande, E. (1997). "Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro". Cell Biology and Toxicology. 13 (3): 141–53. doi:10.1023/A:1007321227010. PMID 9088624. S2CID 755744.

[2] Chen, Y.; Chang, F.; Lin, Y.; Wang, L.; Chen, J.; Wu, Y.; Wu, M. (2007). "Identification of phenolic antioxidants from Sword Brake fern (Pteris ensiformis Burm.)". Food Chemistry. 105: 48–56. doi:10.1016/j.foodchem.2007.03.055.

[3] イ・インギョン；ソク、スンジャ。キム・ワンギュ;ユン・ボンシク (2006) 「キノコInonotusxeranticus由来のヒスピジン誘導体とその抗酸化活性」。ナチュラルプロダクツジャーナル。69 (2): 299–301 .土井: 10.1021/np050453n。PMID 16499338。

[4] Lee, In-Kyoung; Yun, Bong-Sik (2007). "薬用キノコのイノノトゥス属とフェリヌス属に含まれる、ヒスピジン系抗酸化物質の多様性を提供する高酸素化および不飽和代謝物". Bioorganic & Medicinal Chemistry . 15 (10): 3309–14 . doi : 10.1016/j.bmc.2007.03.039 . PMID 17387019 .

[pmid18827365-5] Lee, Yeon Sil; Kang, Young-Hee; Jung, Ju-Young; Lee, Sanghyun; Ohuchi, Kazuo; Shin, Kuk Hyun; Kang, Il-Jun; Park, Jung Han Yoon; et al. (2008 年 10 月). " Phellinus linteusの子実体からのタンパク質糖化阻害剤" . Biological & Pharmaceutical Bulletin . 31 (10): 1968– 72. doi : 10.1248/bpb.31.1968 . PMID 18827365 .

[1]

[2]

[3]

[4]

[5]

See also

References